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Reactive oxygen and nitrogen species-induced protein modifications: implication in carcinogenesis and anticancer therapy

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Laugier-Hunziker syndrome: case report and treatment with the Q-switched Nd-Yag laser

It was more effectively activated by elevated levels of GSH in H1299 lung cancer cells than that in normal lung fibroblasts WI38 cells, releasing reactive alkoxyamines to capture AP sites, blocking APE1 repair, and leading to lung cancer cell death in vitro