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Full-text article Dimet-Wiley AL, Latham CM, Brightwell CR, et al

8 A case-control study that compared 25,956 patients who had vitamin B 12 deficiency with 184,199 control patients found a significantly increased risk of vitamin B 12 deficiency in patients who had taken proton pump inhibitors (odds ratio = 1.65) or histamine H 2 blockers (odds ratio = 1.25) for at least two years

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Researchers have asked whether certain signaling peptides could accelerate angiogenesis (new blood-vessel growth), enhance fibroblast recruitment, or improve collagen organization