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The approval marks the fourth NSCLC indication for Tagrisso, which is also authorized for the first-line treatment of metastatic disease, as an adjuvant therapy after resection and in metastatic NSCLC that has progressed after EGFR tyrosine kinase inhibitor (TKI) treatment

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It also instructs patients to inform healthcare providers of planned surgeries or procedures because of reported pulmonary aspiration during general anesthesia or deep sedation