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Furthermore, the current status of clinical trials (collected from clinicaltrials.gov) of the N-to-B delivery systems for several CNS disorders/diseases, including proteins and peptides, was discussed by Pandey et al

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doi:10.1074/jbc.M001706200

Eur Rev Med Pharmacol Sci 21:112121 Lin CH, Lane HY (2019) Early identification and intervention of schizophrenia: Insight from hypotheses of glutamate dysfunction and oxidative stress

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Next, a specialized transport antiporter protein called Carnitine-Acylcarnitine Translocase (CACT) ferries this acylcarnitine complex across the impermeable inner membrane and deep into the mitochondrial matrix, while simultaneously pumping a free L-carnitine molecule back out to maintain the cycle