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In vitro, ipamorelin released GH from primary rat pituitary cells with a potency and efficacy closely comparable to GHRP-6 achieving an EC50 of 1.3 0.4 nmol/L and an Emax of 85 5% relative to GHRP-6's 100% reference maximum

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Additionally, while the most common side effect was mild to moderate gastrointestinal upset, there were fewer events per 100 patients across all of the cagrilintide treatment groups in comparison to the subjects receiving 3.0 mg of liraglutide [1]