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Nuclear cataract was observed in patients treated with hyperbaric oxygen therapy, 55 and markedly elevated levels of mature cataract were observed in mice that survived exposure to 100% oxygen twice weekly for 3 hours

Total cholesterol levels in HFD-fed mice were significantly higher compared to the levels in control diet group

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Direct answer: Yes, current data suggests it remains safe with proper monitoring

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Glucose starvation could induce massive death of glioblastoma cells under temozolomide (TMZ) or carboplatin treatment, but a small subset of cells escapes and becomes persistent to these chemotherapeutic drugs, entering a quiescent state by enhancing autophagy 133