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When taken orally, L-Carnitine should be safe to take for up to 12 months, and it is most commonly used in doses of 2 grams daily (WebMD)

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In their 2017 position stand, the ISSN concluded that creatine monohydrate is safe and effective for adolescent athletes (ages 16+), provided they are involved in serious/competitive supervised training, are consuming a well-balanced diet, and use the supplement under appropriate guidance [11]

That has morphed into claims about anti-aging benefits and immune system boosts