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Meanwhile, toxins stored in rapidly shrinking fat cells release into the body and need more B2, B6, and Folate to prevent damage

In addition, the complete oxidation of glucose to acetyl-CoA, by the pyruvate dehydrogenase complex (PDHc), provides the acetyl-CoA necessary for de novo synthesis of free fatty acids

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Clinically, this condition presents with a characteristic saturation gapdiscordance between pulse oximetry and arterial co-oximetryalong with cyanosis and chocolate-brown blood discoloration, typically triggered by oxidative drugs such as dapsone, benzocaine, or nitrates