l-carnitine effect on cholesterol Dietary accelerates atherosclerosis and inhibits reverse Carnitine, Choline, Cancer, & Cholesterol:

Underlying mechanisms of apoptosis in HepG2 cells induced by polyphyllin I through Fas death and mitochondrial pathways

In contrast, very large supplemental doses of pyridoxine 2,000 mg per day or more are linked to sensory nerve damage and skin lesions ( High intake of pyridoxine supplements may also suppress milk production in breastfeeding women ( Benefits of Supplements Large doses of pyridoxine have been used to treat carpal tunnel syndrome and premenstrual syndrome

Fuan Pharmaceutical replies quickly

They were treated with four different types of GLP-1RAs

The mechanistic evidence is strong

This is not a complete list of possible side effects