Cellular senescence: It is a form of self-defense mechanism where there is a pause in cell division, but there isnt permanent death
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Studies demonstrate that Sch B activates autophagy via the AMPK/mTOR pathway, reducing lipid droplet accumulation in free fatty acid (FFA)-treated HepG2 cells and mouse primary hepatocytes (MPH), thereby inhibiting hepatic steatosis, enhancing fatty acid oxidation (FAO), and preventing NAFLD (Yan et al., 2022)
Furthermore, the DPP-4 inhibitor MK0626 has been shown to increase IL-10 levels (34)
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