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We conclude that axonal injury differentially regulates surface expression of synaptic and extrasynaptic NMDARs as well as of NR2A and NR2B subunits in neonatal HMNs, which results in an elevated NR2B/NR2A ratio at the synaptic and extrasynaptic membranes

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A.TuckerS.GhofraniJ.et al (2016)

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After your first injection, levels rise and then start declining according to the seven-day half-life