In states of insulin resistance, hepatic steatosis, and renal impairment, mitochondrial electron transport chain dysfunction drives the excessive production of ROS, which results in redox imbalance and metabolic stress (96, 97)
These issues can affect everything from your joints to your nails even your nervous system and can have a major impact on quality of life
Brundert M, Heeren J, Merkel M, Carambia A, Herkel J, Groitl P, Dobner T, Ramakrishnan R, Moore KJ, Rinninger F
Diabet Med 1998;15:297-303.ArticlePubMed 45
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FIGURE 8 4 Conclusion Nanoparticles were plagued by various biological obstacles in clinical practice, especially the RES effect of macrophages, which led to a large amount of nanoparticle aggregation in the liver