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In a meta-analysis 6 of eight trials with 60080 patients (ELIXA, LEADER, SUSTAIN-6, EXSCEL, Harmony Outcomes, REWIND, PIONEER 6, and AMPLITUDE-O) , treatment with a GLP-1 receptor agonist led to a 14% relative risk reduction in three-point MACE (HR 086 [95% CI 080093]

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Patients who experience side effects should report them to their healthcare professional or directly to the MHRA through the Yellow Card scheme (yellowcard.mhra.gov.uk)

If you have had a cardiac event and you are also overweight, this is often a better coverage path than the Bridge because the drug cost counts toward your annual out-of-pocket cap