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When glutathione levels are adequate, this cycle efficiently neutralizes the HO generated during thyroid hormone synthesis

We found an indirect effect of GLP-1RAs on SA through BMI(OR 0.86 [95%CI 0.751.00], P = 4.56 10 2 ), with a mediation proportion of 20.28% (95% CI [0.3740.16%]),and through current tobacco smoking (OR 0.95 [95%CI 0.910.99], P = 2.75 10 2 ), with a mediation proportion of 6.65% (95%CI [0.74%12.57%]).The mediating effect of alcohol consumption was not observed (P = 1.29 10 1 ) (Fig

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The combination therapy exhibited enhanced efficacy compared to monotherapy across multiple parameters, suggesting complementary mechanisms of action

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