glp-1 dietitian Nutrition: What Dietitians Need to Know A registered dietitian has advised

How Trulicity works Trulicity mimics one hormone called GLP-1 (glucagon-like peptide-1), which: Slows food movement through your stomach, helping you feel fuller for longer Communicates with your brains appetite centre to reduce hunger Improves blood sugar control by enhancing insulin function How Mounjaro works Mounjaro activates two hormone receptors: Like Trulicity, it activates the GLP-1 receptor It also activates GIP (glucose-dependent insulinotropic polypeptide), a second gut hormone involved in appetite and blood sugar regulation This dual-action is the primary reason Mounjaro produces greater weight loss and blood sugar improvements than GLP-1-only medications like Trulicity

Implement structured meal timing: eat every 34 hours, never skip breakfast, and avoid grazing or snacking between meals

By restoring cellular methyl donor capacity, it may support genomic stability and longevity-associated gene expression patterns

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This once-daily tablet is prescribed as monotherapy or in combination with other diabetes medications when diet, exercise, and existing treatments do not achieve target HbA1c levels

First, the diversity of the gut microbiota itself appears to determine MAIT cell activation