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Acknowledgements The authors would like to thank every researcher that contributed to the understanding of the close relationship between the IGF-1 deficiency and the Metabolic Syndrome establishment

described this reduced effect with GIP and not with GLP-1, because at that time GIP was the only incretin known

Glutathione controls specialized immune cells, called T regulatory cells (13)

Hattersley, G., Dean, T., Corbin, B

Lower blood sugar levels reduce the risk of diabetes complications, including nerve damage, vision problems, and kidney disease

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