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doi: 10.1016/j.semnephrol.2021.03.005 114 LeeY

Patients with prediabetes, obesity, or metabolic syndrome could potentially receive treatment sooner, particularly if clinical evidence continues to support cardiovascular and renal benefits

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Receptor Pharmacology PMC open access Central MCR mechanism confirmed by SHU 9119 antagonism Central effects of Melanotan II shown to be abolished by SHU 9119, a non-selective MC3R/MC4R antagonist, confirming receptor-mediated central MCR mechanism

Doctors may also use semaglutide to treat overweight and obesity

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