[DOI] [PubMed] 14.Goh KK, Chen CH, Lu ML.Topiramate mitigates weight gain in antipsychotic- treated patients with schizophrenia: meta-analysis of randomised controlled trials
The main critical improvements are modification of residues in the peptide backbone to obtain GIP receptor-activating activity, prolongation of the C-terminus with a sequence of C-terminal of exenatide, and conjugation of the fatty acid side chain to prolong half-life (116.7 h) [30,44]
15 Dual GLP-1 and GIP agonists are expected to have more profound effects
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Additionally, individuals without insurance coverage or with inadequate coverage may face higher retail prices for these medications
Journal Reference : Robert Bozick, Shannon D