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A recent Nature article reports a preclinical GLP-1GIPlanifibranor conjugate: a unimolecular quintuple agonist designed to combine GLP-1R/GIPR co-agonism with PPAR// agonism

Stick to proven formulations with established dosing and safety profiles.

To overcome the challenges of digestion, advanced delivery methods are necessary

We focus on what matters for GLP-1 users: getting enough protein to protect your muscle

However, it contains a cyanide molecule that the body must remove during metabolism

Patients have reported decreased interest in alcohol and nicotine when taking GLP-1s, and observational studies have shown an association between treatment with GLP-1 medication and lower risk of alcohol and cannabis use disorders, opioid overdose, and alcohol-related hospitalization