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Side Effects & Safety Topical copper peptides are generally well tolerated in cosmetic use, with the main documented concerns being local: irritation, redness, or, less commonly, allergic contact dermatitis

After 4 weeks, the dose is increased to 0.5 mg per week

doi: 10.1080/15548627.2021.1885203 93 YuZZhaoGLiPLiYZhouGChenYet al

The mechanism is documented across multiple systematic reviews

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