S-adenosylmethionine (SAMe) as treatment for depression: a systematic review
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Although absorption difficulties and other medical issues often cause low vitamin B12 levels, some people may be deficient because they do not get enough vitamin B12 from their diet
This is particularly relevant for oral administration, which is subject to intrinsic factor saturation and receptor limitations in the ileum ( Moreover, our results highlight the essential role of vitamin B12 in homocysteine metabolism, as supplementation was associated with a significant reduction in serum homocysteine levelsan important biomarker associated with cardiovascular and neurodegenerative diseases