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Li and colleagues [152,153,154] Recently, it has been demonstrated that intravenous administration of etanercept to transgenic AD mice (3xTg) significantly enhances spatial, long-term, and working memory, as assessed by behavioral tests (Morris water and Y-maze tasks)

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In addition to fisetin and Q, other natural substances derived from plants also exhibit senolytic properties, such as piperlongumine (PL) and its analogues (56), or the curcumin analog EF24 (57)

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doi: 10.1016/j.biopsych.2018.08.018 138 RohlederN