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Some community members are running this sequence deliberately: start with NAD+ precursors (NMN/NR) to raise the baseline pool, then add MOTS-C to put that pool to work, then layer in 5-Amino-1MQ to block the pathway that drains it

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That may be a rational design for local GI exposure , where systemic bioavailability may not even be the primary objective

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So, when you're mapping out your next study on shoulder recovery, remember the principles