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The authors discuss whether CNS injection of the drug versus systemic treatment may play an important role in the overall effect

10.1146/annurev-micro-020518-120210 21

Not suitable for children, those sensitive to caffeine, like pregnant or nursing individuals.

Levocarnitine was not bound to plasma protein or albumin when tested at any concentration or with any species including the human.9 In a pharmacokinetic study where five normal adult male volunteers received an oral dose of [3H-methyl]-L-carnitine following 15 days of a high carnitine diet and additional carnitine supplement, 58 to 65% of the administered radioactive dose was recovered in the urine and feces in 5 to 11 days

The intensity of these changes can vary significantly from person to person, reflecting individual physiological responses and previous dietary habits

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