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PMID: 76 KarasawaTChoiRHMezaCAWatanabeSMaschekJANikolovaLSet al

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Compounded tirzepatide works the same way the standard tirzepatide works for weight loss

In animal models, GLP-1R agonists prevent capillary rarefaction and microvascular barrier dysfunction and reduce apoptosis and reactive oxygen species in microvascular endothelial cells, contributing to improved organ function and reduced progression of microvascular complications [162]

Furthermore, the expression of GLP-1 receptor in obese subjects (middle panels) was much lower compared to non-obese subjects (upper panels)

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