RESULTS: Over a mean follow-up of 47.510.9 months, the risk of the primary outcome in the overall trial population was 14% lower for oral semaglutide versus placebo (hazard ratio, 0.86
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Interestingly, our findings also revealed that treatment with N-3 PUFAs alone increased VDR expression three-fold, This finding highlights the potential of N-3 PUFAs to enhance VDR expression independently, which could represent a novel way of neuroprotection, suggesting an additional mechanism for the synergistic neuroprotective effect observed in rats receiving the combined treatment, that was primarily associated with reduced neuronal apoptosis, tauopathy, and proinflammatory status in the brain
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" GLP-1
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