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Louradour et al., 2017), activation of the Wingless signaling pathway (Sinenko et al., 2009) and expression of the EBF transcription factor Collier (Benmimoun et al., 2012

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Cytochrome P450 4F2 (CYP4F2) initiates -oxidation of tocochromanols, a process that is followed by -oxidation to carboxyethyl hydroxychromanol (CEHC), which can be conjugated with glucuronide or sulfate and excreted in urine or bile

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Regular use supports detoxification, reduces oxidative stress, and improves skin health

The result is spent or oxidised glutathione (GSSG)