The reported effects were not dose-dependent
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Interestingly, injecting mice with 400 ng of recombinant mouse IL-6 twice daily for 7 days significantly increases fasting plasma active GLP-1, as well as ileal Gcg and Pcsk1 mRNA, but not plasma GLP-2 (ELISA) or DPP4 activity (Ellingsgaard et al., 2011)
Your GP should monitor: Weight trends and body composition changes Blood glucose and HbA1c levels Blood pressure (both medications can influence cardiovascular parameters) Electrolyte balance (prednisolone can cause hypokalaemia) Bone health if long-term corticosteroid use is anticipated (following NOGG guidance for glucocorticoid-induced osteoporosis risk assessment and prophylaxis) Never stop either medication without medical guidance
Ferroptosis inhibitors have also been shown to ameliorate HSC deficiencies in MYSM1 function loss (Zhao et al., 2023)
The p38 MAPK inhibitors for the treatment of inflammatory diseases and cancer