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Finally, the primary outcome is a surrogate measured during a short follow-up period. They are also honest: We are, therefore, not able to draw conclusions about the longer-term effects of semaglutide in this population. And they conclude that: These findings support future clinical trials to assess the efficacy of semaglutide in reducing the risk of kidney failure and cardiovascular complications in these patients. I would characterize that as a reasonable conclusion given the limitations

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