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It is interesting to note that the positive effect of tirzepatide on body weight is associated with a significant improvement in quality of life and physical performance [50] and is independent of sex [51], baseline body mass index (BMI) [52] and potential side effects, predominantly gastrointestinal [53]

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Cochrane Database Syst Rev (2020) 7(7):CD012990

The most commonly reported side effects in trials are gastrointestinal: nausea, vomiting, diarrhoea, constipation, and decreased appetite

[DOI] [PubMed] [Google Scholar] 37.Neumann E, Junker S, Schett G, Frommer K, Mller-Ladner U

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