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We have identified candidate HPX receptors and human proteins that bind to hemeHPX, i.e., HPX interactomes, in a human neutrophil model (promyelocytic HL-60 cells), in hepatoma HepG2 cells, and in primary human hepatocytes

Phase III RELAX-AHF A phase III study was conducted with the same inclusion criteria as Pre-RELAX-AHF, aiming to investigate whether patients treated with serelaxin would experience greater dyspnea relief than patients treated with SoC and placebo [24]

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