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All metabolite identifications were assigned as putative (MSI Level 2), in accordance with the Metabolomics Standards Initiative (Sumner et al., 2007), as authentic standards were not analyzed under matched chromatographic and instrumental conditions

Phase 2 trial - Lancet, 2023 Receptor systems the peptide acts on - GLP-1, GIP and glucagon - which is why it's studied as a 'triple agonist'

Most peptides remain stable at 2, 8 C for 28 to 30 days after reconstitution

These are standard practices for all peptide users, but the consequences of contamination are more severe for autoimmune patients

doi: 10.1126/scitranslmed.abi4632 149 TurnerBCreeBACKapposLMontalbanXPapeixCWolinskyJSet al

We're seeing more and more studies leverage this prolonged effect to understand long-term metabolic adaptations, a demanding, often moving-target objective in this field