98 %
PAMPs from persistent pathogen components and DAMPs from mitochondrial stress synergistically activate the NLRP3 inflammasome and NF-B pathway, which are the core innate immune pathways mediating the conversion of metabolic stress into systemic inflammation
Tabata et al., 1999) are illustrative for the pertinence of the poorly resolved problem, illustrative for the diversity of the carriers (i.e., hyaluronate gel carrier (Wang and Aspengberg, 1996), alginate/heparinsacharose microspheres and films (Yu et al., 1998), cellulose gel (Thorn and Aspenberg, 1993), defective form of Pseudomonas exotoxin (Siegall et al., 1994), fibrin adhesive carrier (Walter et al., 1996), biodegredable hydrogen gelatin (Tabata et al., 1999), natural coral, and collagen (Sikiric et al., 2018), there is an inescapable diversity of the carriers and thereby, an evident diversity of the obtained beneficial effects, and disable conclusion
GLS-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the redox state, stemness and ATG5-mediated autophagy
This may help calm an overactive surge
Sci Transl Med 2013;5:209ra151
