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FIGURE 5 The in vitro experiment indicated UA induced cytoplasmic lipid deposition could be rescued by exogenous LC supplement while be exacerbated by TMZ

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Mechanism Overview (Research Context) Retatrutide Retatrutide is studied as a multi-receptor agonist interacting with GLP-1, GIP, and glucagon receptors

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Cells expressing APEX2-GFP were enriched by fluorescence-activated cell sorting (FACS), and cells expressing mito-APEX2 were enriched by puromycin selection