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In relation to this, when a patient undergoes a weight loss surgery, gastrointestinal surgery, or plastic surgery, their bodys ability to absorb vitamin B12 usually is compromised for a while

Studies indicate that long-term metformin use can reduce serum B12 blood test levels by up to 20%, necessitating regular monitoring and preventive B12 supplementation protocols

Its overall effects on the gut include regulating the GI microbiome, improving the functions of the intestines, and reducing constipation

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