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Butyrate rescues PBAT-MPs-elicited microglial lipotoxicity and neurodegeneration via the gutbrain axis To validate our in vitro findings in vivo, C57BL/6 mice were exposed to PBAT-MPs with or without butyrate (200 mM) in drinking water for 4 weeks

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Nature 424 : 561565 Lee TH, Kim SU, Yu SL, Kim SH, Park do S, Moon HB, Dho SH, Kwon KS, Kwon HJ, Han YH, Jeong S, Kang SW, Shin HS, Lee KK, Rhee SG and Yu DY (2003) Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice