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There is evidence in other cancer types that point towards using wildtype IDH1 inhibition in combination with chemotherapy as a strategy for treatment, although these studies focused on redox balance and ROS (Vaziri-Gohar et al., 2022

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Biol Neonate 84 : 142146 Te Braake FW, Schierbeek H, de Groof K, Vermes A, Longini M, Buonocore G, van Goudoever JB 2008 Glutathione synthesis rates after amino acid administration directly after birth in preterm infants