[DOI] [PMC free article] [PubMed] [Google Scholar] 65.Pejic S., Kasapovic J., Todorovic A., Stojiljkovic V., Pajovic S.B
The pharmacology of the TMEM16A channel: therapeutic opportunities
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(2022) Overproduction of hydrogen sulfide, generated by cystathionine -synthase, disrupts brain wave patterns and contributes to neurobehavioral dysfunction in a rat model of down syndrome
Collectively, GGCT functions as a metabolic rheostat that orchestrates mitochondrial homeostasis through diverting Gln flux toward glutathione biosynthesis to fortify redox defense, while enhancing Glc-fueled TCA cycle anaplerosis to sustain cell proliferation
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