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Consequently, evidence supporting essentiality is assembled on the AOP page, rather than on the independent KE pages that are meant to stand-alone as modular units without reference to other KEs in the sequence

Dementia and Alzheimer's are experiencing a shift in the way we understand the science and treat the disease manifestations

The GLP-1 receptor agonist semaglutide significantly improved symptoms and walking distance in patients with claudication

Glycine and aging: Evidence and mechanisms

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This leads to increased bile acids in the intestinal lumen, which then trigger Takeda G-protein-coupled receptor 5 (TGR5) on L-cells, stimulating the production and release of GLP-1 (Thomas et al., 2009