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When the rectum becomes distended with stool, it can press against the bladder, reducing its capacity and preventing complete emptying

Incidence of gastric ulcer in albino rats fed diets deficient in vitamin B1

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doi:10.1016/j.eclnm.2011.02.001 30 Smedberg M

Patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) should discuss these conditions with their doctor before starting treatment, as GLP-1 receptor agonists have been associated with thyroid C-cell tumours in animal studies, though human relevance remains uncertain

Sections were then incubated for 1 hour at room temperature with fluorescent secondary antibodies (ab150080, Alexa Fluor 594 goat antirabbit IgG, 1:1,000