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So there are so many complicating factors, and I just commend you for trying to at least shed some light on this complicated issue that I think practitioners tend to simplify just because otherwise, it's too overwhelming to treat to be honest

10.4049/jimmunol.0803600 48

Kataura, T

Pharmacology & Therapeutics, 109 (3), 325-338

For multi-arm studies, pairing Pal-GHK-Cu with GHK-Cu (50mg) from the same supplier eliminates inter-vendor purity variability and tightens experimental controls considerably

Systemic conditions like rheumatoid arthritis, gout, and psoriatic arthritis can also drive bursitis and if one of these is involved, local treatment alone won't hold long-term without managing the underlying disease