The present mini-review therefore aims to summarize the contribution of ED to CVD in obesity and T2DM, to synthesize the pre-clinical and clinical evidence supporting endothelial and cardiovascular benefits of GLP-1RAs, and to delineate current controversies and research priorities that will inform future incretin-modulating interventions
Long-term success depends on viewing semaglutide as one part of a broader strategy that includes nutrition, physical activity, and medical follow-up
It is typically treated with vitamin B12 injections rather than standard oral supplements
No unique adverse effects emerge from combining these therapies compared to GLP-1 monotherapy
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Traditional tablets provide measured B12 doses swallowed with water