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Unlike synthetic hormones, peptides work by stimulating your own system instead of replacing it

These transcriptional effects of SREBP include (but are not limited to) increased expression of glucokinase (encoded by GCK), liver pyruvate kinase (encoded by PKLR), lipoprotein lipase (encoded by LPL), fatty acid synthase (encoded by FASN), and acetyl-CoA carboxylase 1 (encoded by ACACA), and decreased expression of glucose 6-phosphatase (encoded by the G6PC gene), fructose 1,6-bisphosphatase (encoded by FBP1), and mitochondrial phosphoenolpyruvate carboxykinase (encoded by PCK2)

Beguerie JR, Xingzhong J, Valdez RP

Sleep improvement: THC can improve sleep quality, often disrupted by hot flashes and night sweats

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A separate study addressing oxidative stress mechanisms, Pickart et al