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In the presence of esterases and iron, ROS react with PUFA-PLs in the cell membrane, triggering the production and accumulation of lipid peroxides, which subsequently promote cell death [89]

Takahashi S, Rousseau RF, Yotnda P, Mei Z, Dotti G, Rill D, Hurwitz R, Marini F, Andreeff M , Brenner MK

Animal Model:Male Wistar rats (200-225 g, 13-14 weeks old), skin flap model and full-thickness skin wound model [4] Dosage:For the skin flap model, 100 mg/kg (dissolved in drinking water)

Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin

Peptides are short chains of amino acids that function as signaling molecules in the body

May-Panloup P, Chretien MF, Malthiery Y, Reynier P