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The cerebrovascular system itself also plays a critical role in allowing the transport of nutrients, such as glucose and fatty acids (FA), from the periphery to the brain, for supporting neuronal and glial energetic needs

Kerley RN, McCarthy C, Kell DB, et al

Although a greater understanding of the role of nutritional medicine for migraine is needed, a considerable body of clinical evidence already exists, and could inform clinical practice in a way that improves patient outcomes and reduces suffering associated with the disease

Support for detoxifying and cleansing the body

By supporting these essential cellular processes, NAD+ helps maintain tissue and metabolic homeostasis, promoting healthy aging

Kraemer et al., 2020) and altering the expression of thousands of genes, many of which are involved in the regulation of skeletal muscle structure, fiber type (Dubois et al., 2013), and mRNA transcription (MacLean et al., 2008) (Figure 1)