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This difference influences how quickly you feel appetite suppression and how your body responds to dose increases

These medications can be highly effective for GLP-1 weight loss, helping regulate appetite and support metabolic health

If your dose becomes "supratherapeutic" (too high for your body's needs), you may experience symptoms of iatrogenic hyperthyroidism (an overactive thyroid caused by medication)

GLP-1 agonists are more effective than placebo in HbA1c reduction (7.47% vs

Clinical trials show average reductions of 14% to 16% of initial body weight with Semaglutide and 18% to 21% with Tirzepatide over 68 to 72 weeks

trials assessed 12 mg as the highest maintenance dose [1] [3]