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Two authors (SE and NE) independently assessed the risk of bias in studies across six domains: random sequence generation (selection bias for controlled trials), allocation concealment (selection bias for controlled trials), blinding of participants and personnel (performance bias), blinding of outcome assessment (detection bias), incomplete outcome data (attrition bias), and selective reporting (reporting bias) ( Evidence synthesis We adopted systematic methods, including textual descriptions and tabulation, using the Review Manager (RevMan) (Version 5.4

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As insulin levels normalize and drop from previously elevated states, IGF-1 levels may also decline

Mild to moderate gastrointestinal issues have also been documented as side effects, which can also affect digestion and nutrient absorption

We assess each patients medical history during an initial consultation to tailor treatments and avoid adverse reactions

Someone experiencing severe brain fog and low energy requires different support than someone primarily focused on trouble losing weight