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It's measurable increases in blood pressure (812mmHg systolic elevation reported consistently) and joint discomfort from capsular distension

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Researchers noted that when CJC-1295 was injected along with hGRF129 amide and CJC-1288, it caused acute GH secretions in all animals and produced the largest plasma AUC of GH over a 2-h period of all peptides [4]

IL-6 is a trigger factor for systemic inflammation

Rotating injection sites each week prevents tissue damage and scar formation, which can make future injections more difficult and increase vascular injury risk