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The aging process is marked by a persistent dysregulation between pro-oxidant and antioxidant mechanisms, resulting in the excessive production of ROS that hinder eNOS functionality, diminish NO bioavailability, and exacerbate endothelial dysfunction (19)

RIF: J-00021500-6

Drug Targets 12 (4), 556562

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Utilizing a well-tolerated strain, Bacillus Coagulans is strong and stable enough to survive stomach acid, retain its potency in the intestines, and is an excellent choice for acute events and recovery, such as after antibiotic use.* BIOTE SERENE This nutraceutical includes dihydrohonokiol-B (DHH-B), a potent, stress-relieving extract derived from magnolia tree bark to help relieve feelings of anxiousness quickly.* The Science Behind Biote Serene The active ingredient in Serene, DHH-B, is a polyphenolic compound derived from magnolia tree bark that exerts neuroprotective and anxiolytic properties through a variety of mechanisms

Covariates The TriNetX platform was utilized to conduct a 1:1 propensity score matching (PSM) for characteristics and comorbidities to ensure balance between cohorts