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Orange Book listings of questionable eligibility create regulatory and litigation exposure that diligence must flag

Literature Screening Articles captured from the literature search were uploaded onto the Covidence platform (Cochrane, United Kingdom)

Among adults who have used these drugs, seven in ten say they used them primarily to treat a chronic condition like diabetes or heart disease (38%) or to both treat a chronic condition and lose weight (32%), while three in ten GLP-1 users (30%) report using these drugs primarily to lose weight

Fang, X., et al., -Lipoic Acid Alleviates Hepatic Lipid Deposition by Inhibiting FASN Expression via miR-3548 in Rats

It treats provider assessment of your own history as the deciding factor

Key Report Takeaways By brand, the Ozempic segment led with a 65.31% share of the semaglutide market in 2025